Evaluation of Reduction Mammaplasty Outcomes in Benign and Malignant Indications: A Single-Center Retrospective Comparative Study
İksan Taşdelen11Department of General Surgery, Fatih Sultan Mehmet Training and Research Hospital, İstanbul, Türkiye
Objectives: Reduction mammoplasty is performed for symptomatic macromastia and breast malignancy, yet direct comparisons between these indications are limited. This study compared their perioperative and oncological profiles and examined the relationship between resection weight and preoperative functional impairment. Methods: This single-center retrospective study included 63 women undergoing bilateral reduction mammoplasty between July 2020 and July 2026: 42 for benign macromastia and 21 for malignant indications. Demographic, operative, complication, and oncological data were reviewed. Preoperative activity restriction was graded from none to severe. Associations between resection weight, clinical variables, and activity restriction were analyzed. Results: Groups were comparable in age, body mass index (BMI), weight, smoking, diabetes, resection weight, operative time, and complication rates. Inferior pedicles were more frequent in malignant cases (76.2% vs. 31.0%, p=0.001), reflecting tumor location. Overall complication rate was 7.9%, with no nipple–areola complex necrosis or reoperation. Resection weight correlated with BMI (?=0.51) and operative time (?=0.50; both p<0.001) and increased progressively with activity restriction (530–2240 g, p<0.001). This association remained significant after BMI adjustment (partial ?=0.33, p=0.010). Conclusion: Reduction mammoplasty showed comparable perioperative outcomes across indications. Greater functional limitation was independently associated with larger resection weight. Keywords: Breast cancer, macromastia, oncoplastic breast surgery, reduction mammoplasty
Cite This Article
Taşdelen İ. Evaluation of Reduction Mammaplasty Outcomes in Benign and Malignant Indications: A Single-Center Retrospective Comparative Study. EJMI. 2026; 10(4): 550-558
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