Objectives: This study aims to compare C-reactive protein/albumin ratio (CAR) and neutrophil/lymphocyte ratio (NLR) in predicting mortality in emergency department patients aged 65+. Methods: This prospective study examined patients aged 65+ presenting to the emergency department from September- December 2021. Neutrophil, lymphocyte, C-reactive protein, and albumin measurements were obtained to calculate CAR and NLR and investigate their relationship with mortality. Results: Of 609 patients studied, 282 (46.3%) were admitted to inpatient units and 327 (53.7%) to intensive care. 510 patients (83.7%) were discharged, while 99 (16.3%) died within 4 weeks. Median CAR was significantly higher in deceased patients (3.23) compared to survivors (0.48). Similarly, median NLR was significantly higher in deceased patients (9.55) versus survivors (5.64). Conclusion: Both CAR and NLR effectively predict mortality in elderly emergency patients, with CAR demonstrating superior effectiveness as a biomarker for determining mortality risk compared to NLR. These findings suggest that CAR could be a valuable tool for risk stratification in the emergency care of elderly patients. Keywords: Emergency Department, CRP/Albumin Ratio, Neutrophil/Lymphocyte Ratio
Corresponding Author: Ali İhsan Kilci