Proportion of Breast Cancer Patients with SARS-CoV-2 Infection during the COVID-19 Pandemic: A Systematic Review and Meta-Analysis
Soheila Sayad1, Nazanin Hajizadeh2, Abolhasan Alijanpour3, Sepideh Azizi4, Meraj Farbod5, Maedeh Barahman61Department of Surgery, Iran University of Medical Sciences, Tehran, Iran, 2Prevention Gynecology Research Center, Imam Hossein Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran Prevention Gynecology Research Center, Imam Hossein Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran, 3Department of Surgery, Babol University of Medical Sciences, Faculty of Medicine, Babol, Iran, 4Akbarabadi Clinical Research Development Unit, Iran University of Medical Sciences, Tehran, Iran, 5Cancer Institute, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran, 6Firoozgar Clinical Research Development Center (FCRDC), Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran Firoozgar Clinical Research Development Center (FCRDC), Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran
The coronavirus disease 2019 (COVID-19) is currently representing a global health threat especially for fragile peoples, such as cancer patients. A few studies have described that people with a breast cancer more likely to be infected with COVID-19. Here, we performed a meta-analysis to assess the proportion of breast cancer patients with SARS-CoV-2 infection during the COVID-19 pandemic. A comprehensive literature search of the PubMed, Web of Sciences, Scopus, MedRxiv, SID, and CNKI database was performed. A total of 26 studies with a total of 6,537 infected cancer patients and 1,093 breast cancer patients with COVID-19 met our inclusion criteria. Pooled data showed that the proportion of breast cancer patients with SARS-CoV-2 infection was 17.1% (95% CI 0.144-0.201) in total infected cancer patients. Stratified analysis showed that the proportion in Caucasian and Asian infected breast cancer patients was 17.6% and 14.5%, respectively. Moreover, the proportion was the highest in France (19.3%) followed by US (19.2%), China (14.8%) and UK (13.8%). Our combined data indicated that the proportion of breast cancer patients with SARS-CoV-2 infection during the COVID-19 pandemic was 17.1%. However, we need to more high-quality and multicenter studies from different ethnicities to draw more accurate findings. Keywords: Breast cancer, COVID-19, infection, proportion, SARS-CoV-2.
Cite This Article
Sayad S, Hajizadeh N, Alijanpour A, Azizi S, Farbod M, Barahman M. Proportion of Breast Cancer Patients with SARS-CoV-2 Infection during the COVID-19 Pandemic: A Systematic Review and Meta-Analysis. EJMI. 2024; 8(3): 145-156
Corresponding Author: Soheila Sayad