Prognostic Factors for Intensive Care Unit (ICU) Admission among Hospitalized Gastrointestinal and Hepatopancreatobiliary Cancer Patients with Systemic Urinary Tract Infection
Tanju Kapagan1, Ferhat Ferhatoglu11Department of Medical Oncology, Basaksehir Cam and Sakura City Hospital, Istanbul, Türkiye
Objectives: Systemic infections in cancer patients are associated with increased intensive care unit (ICU) admissions. In this study, we aimed to determine the vital and laboratory parameters that predict ICU admission in the hospitalized gastrointestinal system (GIS) and hepatopancreatobiliary system (HPBS) cancer patients with urinary tract infection (UTI) during the paliateve treatment. Methods: The files of 305 GIS or HPBS adult cancer patients followed up in the Oncology inpatient Clinic were retrospectively screened. Fifty-eight patients with positive urine cultures were included in the study. Risk factors of clinical and laboratory values associated with ICU admission were analyzed. Results: Of 58 patients 56.8% (n=33) were female. The mean age was 63 years. The most isolated microorganisms in urine culture were Escherichia coli (n=20, 34.4%). In multivariate analysis, low thrombocyte (HR = 1.011, 95% CI 1.001- 1,020, p=0.028) and high urea (HR = 0.973, 95% CI 0.02-0.74, p=0.021) values at discharge were independent prognostic risk factors for ICU admission. Conclusion: In the case of thrombocytopenia and high urea levels in hospitalized GIS and HPBS cancer patients with UTI, preventive measures or treatment of these factors may reduce ICU admission. Keywords: Cancer, urea, thrombocyte, systemic urinary tract infection, intensive care unit
Cite This Article
Kapagan T, Ferhatoglu F. Prognostic Factors for Intensive Care Unit (ICU) Admission among Hospitalized Gastrointestinal and Hepatopancreatobiliary Cancer Patients with Systemic Urinary Tract Infection. EJMI. 2023; 7(2): 107-115
Corresponding Author: Tanju Kapagan