The Importance of Evaluating Hematologic Parameters in the Diagnosis of Acute Appendicitis Among Pregnant Patients
Ilkay Guler1, Umit Ozdemir2, Bulent Comcali3, Izzet Ozgurturk4, Nurgul Balci11Republic of Türkiye, Ministry of Health, General Directorate of Public Hospitals, Ankara, Türkiye, 2Department of General Surgery, Ankara Etlik City Hospital, Ankara, Türkiye, 3Department of General Surgery, Ankara Bilkent City Hospital, Ankara, Türkiye, 4Department of Gynecology and Obstetrics, Ankara Etlik City Hospital, Ankara, Türkiye
Objectives: The most frequently occurring non-obstetric surgical issue during pregnancy is acute appendicitis (AA). The aim of this study was to examine the diagnostic accuracy of hematological parameters such as neutrophil-lymphocyte ratio (NLR), platelet lymphocyte ratio (PLR), red cell distribution width (RDW) and systemic inflammatory index (SII) in the diagnosis of AA among pregnant women. Methods: In this retrospective study, patients were examined in two groups: 52 pregnant patients who underwent appendectomy (appendectomy group) and 156 healthy pregnant women (control group). The diagnostic accuracy of hematology parameters was evaluated by receiver operating characteristic (ROC) curve and logistic regression analysis. Results: According to ROC analysis, the sensitivity and specificity values of WBC, NLR, PLR, RDW and SII were found as follows, respectively: 69.2%, 91.03%; 78.4%, 82.1%; 62.7%, 59.0%; 67.2%, 52.6%; 73.1%, 85.9%. According to the logistic regression model in AA cases in pregnant women, an accuracy rate of 87.9% was determined by using WBC, NLR, PLR and RDW and SII values. Conclusion: Combined evaluation of easily accessible tests such as NLR, PLR, RDW, and SII together with physical examination, anamnesis and imaging methods is useful in the diagnosis of AA in pregnant women. Keywords: Acute appendicitis, hematologic parameters, pregnancy
Cite This Article
Guler I, Ozdemir U, Comcali B, Ozgurturk I, Balci N. The Importance of Evaluating Hematologic Parameters in the Diagnosis of Acute Appendicitis Among Pregnant Patients. EJMI. 2023; 7(4): 460-465
Corresponding Author: Ilkay Guler