Objectives: The differentiation between infectious and tumoral lymph node (LN) causes diagnostic difficulties in lung cancer (CA) patients concurrent with Covid-19 pneumonia. In our study, we evaluated the contribution of CT density and PET/CT SUV max measurements to the diagnosis in the differentiation of mediastinal LNs. Methods: In our retrospective study, 20 lung CA and 20 Covid-19 patients with mediastinal lymph node involvement with PET CT were included. Results: The mean LN density value of the participants in the Covid-19 group was 51±1.45 Hounsfield units (HU), and the mean SUV max value was 4.43±0.47. Of the participants in the lung CA group, on the other hand, the mean density value was 38±8.08 HU, and the mean SUV max value was 8.97±3.07. The difference between the density and SUV max values showed a statistically significant difference. Conclusion: We found that density and SUV max values can make a significant contribution to the differential diagnosis in the differentiation between mediastinal LNs of Covid-19 and lung cancer. Early characterization of lymph nodes in this patient group provides a high prognostic chance. Keywords: Lymph node, density, SUV max
Corresponding Author: Tülin Ozturk