The Assessment of Resistant Hypertension-Related Cardiovascular Risk
Musa Baris Aykan1, Mehmet Esen2, Suat Gormel3, Bilgin Bahadir Basgoz4, Tolga Dogan4, Kenan Saglam41Department of Medical Oncology, University of Health Sciences, Gulhane Faculty of Medicine, Ankara, Turkey Department of Medical Oncology, University of Health Sciences, Gulhane Faculty of Medicine, Ankara, Turkey, 2Department of Radiology, University of Health Sciences, Gulhane Faculty of Medicine, Ankara, Turkey, 3Department of Cardiology, University of Health Sciences, Gulhane Faculty of Medicine, Ankara, Turkey, 4Department of Internal Medicine, University of Health Sciences, Gulhane Faculty of Medicine, Ankara, Turkey
Objectives: The effect of resistant hypertension (RH) on cardiovascular risk has not been clarified. According to the ambulatory blood pressure monitoring (ABPM) results, cardiovascular disease outcomes are more common in patients with non-dipping pattern. We aimed to show cardiac end-organ damages in RH and non-dipping patients within the RH. Methods: RH and regular hypertensive cases were included. Cardiovascular endpoints were determined as carotid intima-media thickness (CIMT), echocardiography parameters, and microalbuminuria. RH patients were divided into dipping and non-dipping groups according to the ABPM and the comparison of end-organ damage among themselves was performed separately. Results: A total of 95 patients were enrolled, 61 in RH group. Significant differences were found between the RH and the regular hypertensive group in terms of CIMT and microalbuminuria (p=0.020 for the right CIMT, p=0.016 for the left CIMT, and p=0.003 for the microalbuminuria). There were no significant differences between the groups in resistant and regular hypertension (HTN) and also dipping and non-dipping groups in RH in terms of other parameters. Conclusion: Significant differences were detected between RH and regulated HTN patients in terms of CIMT and microalbuminuria, but there was no difference between the dipping and non-dipping groups in terms of atherosclerotic burden. Keywords: Carotid intima-media thickness, end-organ damage, hypertension, microalbuminuria, resistant hypertension
Cite This Article
Aykan M, Esen M, Gormel S, Basgoz B, Dogan T, Saglam K. The Assessment of Resistant Hypertension-Related Cardiovascular Risk. EJMI. 2021; 5(1): 125-135
Corresponding Author: Musa Baris Aykan