Efficacy of Gamma-Knife Radiosurgery in Grade 2 and Grade 3 Meningioma: A Single-Center, Long-Term Follow-Up Study
Erkut Taha Bulduk1, Harun Demirci2, Burak Karaaslan3, Oguz Kagan Demirtas3, Omer Hakan Emmez3, Gokhan Kurt31Department of Neurosurgery, Atılım University, Faculty of Medicine, Ankara, Turkey, 2Department of Neurosurgery, Yıldırım Beyazıt University Ankara City Hospital, Ankara, Turkey, 3Department of Neurosurgery, Gazi University, Faculty of Medicine, Ankara, Turkey
Objectives: Gamma-Knife Radiosurgery (GKR) is a safe and effective treatment option in patients who have a high risk of complications in skull base and eloquent area-based tumors, in those to whom total surgery cannot be applied. The purpose was to analyze the results of radiosurgery in patients who underwent GKR for the residues or recurrent tumors in high grade meningiomas. Methods: A retrospective screening was performed on patients who underwent GKR at Gazi University between 2004 and 2018. The gender, mean age, location, volume, complications, size changes after GKR were noted. Results: A total of 35 (79.5%) patients were treated with Grade 2, and 9 (20.5%) were treated with Grade 3 meningiomas. The mean follow-up period was 48 months (3-108). The mean volume was noted as 9339 mm3. The tumor control rates after GKR were determined as 94% in Grade 2 and 55% in Grade 3 meningiomas. Conclusion: GKR can be applied as a safe and effective method for postoperative tumor control in high grade meningiomas. Keywords: Atypical meningioma, high-grade meningioma, malignant meningioma, radiosurgery, gamma-knife
Cite This Article
Bulduk E, Demirci H, Karaaslan B, Demirtas O, Emmez O, Kurt G. Efficacy of Gamma-Knife Radiosurgery in Grade 2 and Grade 3 Meningioma: A Single-Center, Long-Term Follow-Up Study. EJMI. 2021; 5(3): 404-408
Corresponding Author: Erkut Taha Bulduk