Evaluation of PET/CT Parameters and Postoperative Pathology Results in Patients with Laryngeal Carcinoma
Muhammed Gazi Yildiz1, Dogan Cakan21Department of Otorhinolaryngology, Kahramanmaras Sutcu Imam University Faculty of Medicine, Kahramanmaras, Turkey, 2Department of Otorhinolaryngology, Istanbul University Cerrahpasa Faculty of Medicine, Istanbul, Turkey
Objectives: The aim of this study was to invastigate the relation between positron emission tomography/computed tomography(PET/CT) and postoperative pathology findings in larynx cancer. Methods: Fifty patients with larynx cancer were included in the study.The SUVmax values and dimensions of larynx(Mass-SUVmax) and neck lymph nodes(Node-SUVmax) were measured by PET/CT.The specimens were examined pathologically, and the relationship between preoperative PET/CT values and pathology findings of the tumor was examined. Results: The mean age of the patients with lymph node metastasis(65.71±9.20 years) was statistically significantly higher than the patients without lymph node metastasis(60.46±8.72 years)(p<0.05).PET/CT(Mass-SUVmax and NodeSUVmax) levels were found to be significantly higher in patients with lymph node metastasis compared to patients without metastasis(p<0.05). The DFS was found longer than 5 years in 64.0% (n=32) of the patients.A statistically significant relationship was found between the presence of lymph node metastasis and DFS.DFS was found to be shorter in patients with lymph node metastasis(p<0.05).The PET-CT(Node-SUVmax) levels were found to be statistically significantly higher in the poorly differentiated group compared to the well-differentiated group(p<0,05). Conclusion: In our study, we showed that cervical lymph node metastasis was associated with short DFS in patients with larynx cancer, and high PET/CT levels and poor differentiation were associated with lymph node metastasis. Keywords: Disease-Free Survival, Larynx, Lymphatic Metastasis, Neck Dissection, PET-CT
Cite This Article
Yildiz M, Cakan D. Evaluation of PET/CT Parameters and Postoperative Pathology Results in Patients with Laryngeal Carcinoma. EJMI. 2021; 5(2): 263-268
Corresponding Author: Dogan Cakan