Does Platelet Count Affect Survival Outcomes in Patients with Malignant Pleural Mesothelioma?
Ozgur Acikgoz1, Alper Sonkaya2, Kazim Uygun31Department of Medical Oncology, Medipol Mega University Faculty of Medicine, Istanbul, Turkey, 2Department of Medical Oncology, Acibadem University, Istanbul, Turkey, 3Departmant of Medical Oncology, Kocaeli University Faculty of Medicine, Kocaeli, Turkey
Objectives: Malign mesothelioma arises from pleura, peritoneum, pericardium and tunica vaginalis of testis. It is a primary malignant tumor that originates from mesothelial cells. It is seen relatively low but has a high mortality rate. Methods: In this study, we reviewed 41 (Malignant Pleural Mesothelioma) MPM patients who were admitted to Kocaeli University Department of Oncology between 2008 and 2014 retrospectively. Patient data were reviewed from medical records. We retrospectively analyzed the correlation between the clinical characteristics, complete blood count parameters and survival in patients with MPM. Results: Overall survival (OS) of the entire population was 11.5 months (%95 CI; 5.86-17.19) In multivariate analysis we found a statistically significant correlation with platelet count and progression free survival (p=0.001). In our study overall survival was better in left pleura localized primary tumors, early staged tumors and patients with platelet count lower than 400.000 ?l. Conclusion: Early stage disease and low platelet count have a significant prognostic importance at the time of diagnosis. Keywords: Mesothelioma, platelet, survival.
Cite This Article
Acikgoz O, Sonkaya A, Uygun K. Does Platelet Count Affect Survival Outcomes in Patients with Malignant Pleural Mesothelioma?. EJMI. 2021; 5(4): 508-514
Corresponding Author: Ozgur Acikgoz