EJMI. 2020; 4(2): 243-246 | DOI: 10.14744/ejmi.2020.81008

Comparison of Seventh and Eighth Editions of TNM Staging Classification and Evaluation of Survivals in Operated Non-Small Cell Lung Carcinomas:Single Center Experience

Ozlem Ercelep¹, Ozkan Alan², Tugba A. Telli², Tugba B. Tuylu², Rukiye Arikan², Nazim Can Demircan², Derya Kocakaya³, Faysal Dane², Tunc Lacin⁴, Emine Bozkurtlar⁵, Perran Fulden Yumuk^2
1Department of Medical Oncology, Marmara University Pendik Training and Research Hospital, Istanbul, Turkey, ²Division of Medical Oncology, Marmara University Faculty of Medicine, Istanbul, Turkey, ³Department of Pulmonary Medicine, Marmara University Faculty of Medicine, Istanbul, Turkey, ⁴Department of Thoracic Surgery, Marmara University Faculty of Medicine, Istanbul, Turkey, ⁵epartment of Pathology, Marmara University, Faculty of Medicine, Istanbul, Turkey

Objectives: In this study, our purpose was to compare the survivals of the 7th and 8th editions of TNM staging system in non-small cell lung cancer (NSCLC). Methods: We retrospectively compared pathological staging and survival of 209 patients who were operated with the diagnosis of NSCLC between 2006 and 2017. In this study, we did not include metastatic patients, patients receiving preoperative treatment, patients with low grade malignancy and patients with neuroendocrine carcinoma. Results: Three of the 31 stage 1A changed to 1A1, 11 to 1A2, 17 to 1A3; 16 of the 40 stage 1B changed to 2A; 2 of the 38 stage 2B changed to 1B, 21 changed to 3A; 2 of the 41 stage 3A changed to 2B, 7 changed to 3B. When we grouped stages as I, II, III; there was a significant difference in prognostic effects between 7th edition stages (p=0.01) and 8th edition stages (p=0.02). Presence of surgical margin positivity, lymphatic, perineural and vascular invasion were poor prognostic factors (p<0.05). Conclusion: In our study, we observed similar survival rates according to the 7th and 8th editions of TNM staging system which is used in the pathological staging of lung cancers.

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Cite This Article

Ercelep O, Alan O, Telli T, Tuylu T, Arikan R, Demircan N, Kocakaya D, Dane F, Lacin T, Bozkurtlar E, Yumuk P. Comparison of Seventh and Eighth Editions of TNM Staging Classification and Evaluation of Survivals in Operated Non-Small Cell Lung Carcinomas:Single Center Experience. EJMI. 2020; 4(2): 243-246

Corresponding Author: Ozlem Ercelep

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