Association of Monocyte-to-HDL Ratio With Postoperative Atrial Fibrillation After Coronary Artery Bypass Surgery
Gokhan Erol1, Ertan Demirdas1, Ufuk Mungan2, Hakan Kartal1, Huseyin Sicim1, Gokhan Arslan1, Cengiz Bolcal11Department of Cardiovascular Surgery, Gulhane Training and Research Hospital Ankara, Turkey, 2Department of Cardiovascular Surgery, Lokman Hekim University, Akay Hospital, Ankara, Turkey
Objectives: In this study, we aimed to show whether high monocyte/HDL ratio (MHR), which is an important marker of inflammation, predicts atrial fibrillation after coronary artery bypass surgery. Methods: A total of 1980 patients with preoperative sinus rhythm who underwent CABG operation between May 2012 and March 2014; 256 patients who developed POAF and 256 patients who did not develop POAF in the same period were included in the study. Retrospective demographic data, laboratory findings, mortality and morbidity records were compared. Results: In this study, 256 patients were included in each group. The patients with POAF were similar to those without POAF in terms of preoperative and operative characteristics. Comparison of laboratory data of the patients is given in the table, only significant difference was observed in terms of monocyte count and MHR (p<0.001, p=0.005). It was determined a cut-off level of 0.022 for MHR level for predicting POAF with a sensitivity of %71.2 and a specificity of %51.4, in receiver operating charactheristic (ROC) curve analysis; area under the curve: 0.737, %95 CI: 0.628-0.836, p=0.003). Conclusion: This study will contribute to previous studies on prediction and prevention of POAF development. Keywords: Atrial fibrillation, coronary artery bypass surgery, monocyte-to-HDL ratio
Cite This Article
Erol G, Demirdas E, Mungan U, Kartal H, Sicim H, Arslan G, Bolcal C. Association of Monocyte-to-HDL Ratio With Postoperative Atrial Fibrillation After Coronary Artery Bypass Surgery. EJMI. 2020; 4(1): 61-65
Corresponding Author: Gokhan Erol