C-Reactive Protein-Albumin Ratio’s Prognostic Importance in Esophageal Cancer for Survival
Fatma Yalcin Musri1, Ahmet Erkan Bilici2, Melek Karakurt Eryilmaz3, Ozgur Cem Musri4, Sahin Lacin5, Eyup Halit Yardimci6, Selver Isik71Department of Medical Oncology, Medical Park Hospital, Batman, Turkey, 2Department of Pathology, Regional Training and Research Hospital, Erzurum, Turkey, 3Department of Medical Oncology, Necmettin Erbakan University of Medicine, Konya, Turkey, 4Department of General Surgery, Medical Park Hospital, Batman, Turkey, 5Department of Medical Oncology, Yeditepe University, Faculty of Medicine, Istanbul, Turkey, 6Department of Chest Surgery, Regional Training and Research Hospital, Erzurum, Turkey, 7Deparment of Medical Oncology, Regional Training and Research Hospital, Erzurum, Turkey
Objectives: This study is designed to show the importance of C-reactive protein (CRP) to albumin ratio (CAR) in esophageal cancer (EC) prognosis. Methods: 39 patients with stage I-III EC, who were treated between 2012–2019 in Erzurum Regional Training and Research Hospital Oncology Clinic, are scanned retrospectively. The relationship between CAR and overall survival (OS) is evaluated. CAR cut-off value is calculated as 0.5; the patients are categorized and analyzed in two groups as <0.5 and ?0.5. Results: 39 patients’ evaluation with Cox Regression Analysis showed that CAR has statistically significant effect on survival (p=0.005). Increase in CAR is observed with a decline in patient survival. Sex, histology, localization, smoker or non-smoker groups had no statistically significant effect on survival between <0.5 and ?0.5 subgroups. Conclusion: This study made us think that CAR can be a new and promising inflammation based prognostic score in operable EC patients. An easy, cheap, easily accessible marker CAR, supported with large patient series and prospective studies, may prove to have contribution in clinical decision process. Keywords: C-reactive protein/albumin ratio, esophageal cancer, survival
Cite This Article
Yalcin Musri F, Bilici A, Karakurt Eryilmaz M, Musri O, Lacin S, Yardimci E, Isik S. C-Reactive Protein-Albumin Ratio’s Prognostic Importance in Esophageal Cancer for Survival. EJMI. 2020; 4(4): 501-505
Corresponding Author: Fatma Yalcin Musri