Objectives: Carcinoid syndrome is one of the functional neuroendocrin tumor symptom. It is a very rare disease and a little known about this syndrome. We aimed a study that evaluating general characteristics and prognostic factors on survival in NET patients diagnosed with carcinoid syndrome. Methods: All patients diagnosed with neuroendocrine tumor were retrospectively reviewed in our institution. The patients diagnosed carsinoid syndrome were included in this study. General characteristics were recorded. Prognostic factors on survival were analysed with Cox regression. Kaplan Meier method was used for overall survival. Results: Among 450 patients diagnosed neuroendocrine tumor in our hospital, 29 of them (6.4%) were presented with carcinoid syndrome. The univariate analysis revealed that age, high tumor grade and ki67 score were correlated with poor overall survival and the multivariate analyses revealed that older age were correlated with poor overall survival. The median OS were 61 months in all grades and 64 months for grade 1 tumors, 45 (13-76) months for grade 2 tumors, 5 months for grade 3 tumors and there were statistically significant difference (p=0.007). Conclusion: Age, grade, ki67 score are important prognostic factor. Age is an independent prognostic factor that affecting survival in carcinoid syndrome patients. Keywords: Carcinoid syndrome, overall survival, predictive factors
Corresponding Author: Ender Dogan