E-ISSN 2602-3164
ejmi. 2020; 4(2): 269-273 | DOI: 10.14744/ejmi.2020.30288

The Relationship Between the Prognostic Nutritional Index and Overall Survival in Elderly Patients with Epithelial Ovarian Cancer

Atakan Demir1, Ozkan Alan2, Sinan Koca3, Heves Surmeli4
1Department of Medical Oncology, Acibadem University Faculty of Medicine, Acibadem Maslak Hospital, Istanbul, Turkey, 2Department of Medical Oncology, Tekirdag State Hospital, Tekirdag, Turkey, 3Department of Medical Oncology, Medeniyet University Goztepe Training and Research Hospital, Istanbul, Turkey, 4Department of Medical Oncology, Kartal Dr Lutfi Kirdar Training and Research Hospital, Istanbul, Turkey

Objectives: Ovarian neoplasm is the most common cause of mortality in gynecologic malignancies. In this study, we aimed to investigate the prognostic role of pretreatment prognostic nutritional index (PNI) in geriatric Turkish female patients with advanced epithelial over cancer. Methods: We retrospectively collected the data of 116 elderly ovarian cancer patients who treated between 2008 and 2019. The PNI was calculated as following: [(10×serum albumin (g/dL)) + (0.005×total lymphocyte count)]. Results: The median PNI was 44.8. Median OS was 45 months (95% CI: 31.6–58.3) in patients with PNI ?44.8, 79 months (95% CI: 77.6–80.3) in patients with PNI >44.8 (p=0.002). In cox regression analysis, PNI was found to be an independent prognostic factor as affecting overall survival. Conclusion: From this point of view, it may be considered that nutritional status should be evaluated more prominently for predicting prognosis in geriatric population. Keywords: Ovarian cancer; overall survival; prognosis; prognostic nutritional index


Cite This Article

Demir A, Alan O, Koca S, Surmeli H. The Relationship Between the Prognostic Nutritional Index and Overall Survival in Elderly Patients with Epithelial Ovarian Cancer. ejmi. 2020; 4(2): 269-273

Corresponding Author: Demir A.

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