Etiological Investigation Of Patients Visiting A Hematology Polyclinic For Anemia
Hanife Cetinkaya Esen1, Emine Gulturk2, Esra Turan Erkek2, Mehmet Ali Ustaoglu11Department of Hematology, Dr. Lutfi Kirdar Training and Research Hospital, Istanbul, Turkey, 2Department of Hematology, Istanbul University Faculty of Medicine, Istanbul, Turkey
Objectives: Per the World Health Organization, anemia is defined as a hemoglobin level below 13 g/dL in men, below 12 g/dL in nonpregnant women, and below 11 g/dL in pregnant women. Information on patients who visited to our hematology polyclinic with anemia between September 2014 and March 2015 was retrospectively reviewed, and 103 patients were included in the study. Methods: Anemia was classified into three groups: nutritional anemia and anemia due to production inadequacy in group I; anemia due to increase in erythrocyte destruction in group II; and anemia due to bone marrow infiltrating diseases and hematological malignancies in group III. NCSS 2007 & PASS 2008 statistical software programs were used for statistical analysis. Kruskal-Wallis and Mann-Whitney U test for quantitative data and tests of Pearson chi-square and Fisher-Freeman-Halton tests for qualitative data were used for analysis. Results: The mean ages of groups I, II and III were 47.7, 47.5, and 63.3 years, respectively. Additionally, the mean age of group III was significantly higher. HT and DM were present as additional comorbidities in 20% and 35% of anemia cases, respectively. Although the DM ratio was higher in groups I and II, it was notable that all diabetic patients in group III had a diagnosis of MM. There was a statistically significant difference between (median) PLT levels between groups I and III. The mean LDH level in group II, measured as 573.8 U/ml, was found to be higher than that in the other groups. Mean sedimentation rates were detected in groups I, II and III as 40.7 mm/h, 56.43 mm/h and 73.6 mm/h, respectively. Conclusion: Because nutritional anemia was followed by physicians in internal medicine, nutritional anemia was seen at a lower rate in our study than in prevalence studies. For health interpretations, extensive screenings and etiological studies should be performed in anemic patients. Keywords: Differential diagnosis of anemia, etiology of anemia, hematologic malignancies presenting with anemia
Cite This Article
Cetinkaya Esen H, Gulturk E, Turan Erkek E, Ustaoglu M. Etiological Investigation Of Patients Visiting A Hematology Polyclinic For Anemia. EJMI. 2019; 3(3): 173-181
Corresponding Author: Esra Turan Erkek