Comparison of Effects of Low and High Flow Desflurane Anaesthesia on Hemogram Parameters
Hamit Yoldas1, Ibrahim Karagoz1, Ayhan Ekici2, Abdulhamit Es3, Isa Yildiz1, Abdullah Demirhan1, Murat Bilgi11Department of Anesthesiology and Reanimation, Bolu Abant Izzet Baysal University, Faculty of Medicine, Bolu, Turkey, 2Department of Gynecology and Obstetrics, Abant Izzet Baysal University Faculty of Medicine, Bolu, Turkey, 3Department of Business Administration, Abant Izzet Baysal University Faculty of Economics and Administrative Sciences, Bolu, Turkey.
Objectives: To compare the effects of low and high flow desflurane anaesthesia on hemogram parameters in lower abdominal surgeries. Methods: Sixty female patients who underwent lower abdominal surgery under general anaesthetic were included in this prospective study. Patients were randomly divided into two groups, as Group I (low flow) and Group II (high flow), and then compared with each other according to their demographic features and hemogram parameters. Results: Groups were statistically similar, and there were no significant differences in terms of demographic data between the groups (p>0.05). The comparisons of hemogram parameters within the groups showed that there were significant differences in plateletcrit, platelet-lymphocyte ratio and neutrophil-lymphocyte ratio values in Group I (p<0.05). The comparisons of hemogram parameters within Group II showed a statistically significance in plateletcrit and platelet-lymphocyte ratio values. A statistically significant difference was found for red cell distribution width, neutrophil- lymphocyte ratio, platelet-lymphocyte ratio and plateletcrit values between groups for the pre-operative and post-operative values of hemogram parameters (p<0.05). Conclusion: Our study showed that the administration of low flow anaesthesia led to a positive effect on the inflammatory response by lowering neutrophil-lymphocyte ratio, platelet-lymphocyte ratio and red cell distribution width values, in comparison to high flow anaesthesia. Keywords: Desflurane, hemogram parameters, low and high flow anaesthesia
Cite This Article
Yoldas H, Karagoz I, Ekici A, Es A, Yildiz I, Demirhan A, Bilgi M. Comparison of Effects of Low and High Flow Desflurane Anaesthesia on Hemogram Parameters. EJMI. 2019; 3(4): 255-259
Corresponding Author: Hamit Yoldas