Objective: The aim of this study was to investigate the changes in the levels of alanine aminotransferase, aspartate aminotransferase, urea and creatine kinase in cigarette addicts of Royal Jelly supplementatio. Methods: Cigarette addict control group (n = 10) and cigarette addict supplement group (n=10) were divided into two groups. The supplementation group was given liquid royal jelly (n=10/1000 mg/day), which was at the same time every morning for three weeks. In order to determine AST, ALT, urea and creatine kinase levels in both groups, blood samples were analyzed. SPSS 22.0 package program was used for statistical analysis. Paired Sample t-Test was used for the comparison of the pre and post tests of the groups and Independent t-test was used for the comparison of the two groups. Results: In the analysis of AST, ALT and urea levels between the pre-test and post-test of the experimental group receiving royal jelly supplementation and the control group, no statistical significance was found (p>0,05); creatine kinase level was found statistically significant in favor of posttest in experimental group (p<0,05). Conclusion: As a result of this study, royal jelly supplementation at a dose of 1000 mg / day for three weeks did not affect AST, ALT and urea levels in cigarette addicts; creatine kinase level positively. Keywords: Nicotine, royal jelly, enzymes
Corresponding Author: TASDOGAN A.