Objectives: Nondippers hypertension (NDHT) are known to carry a high risk of cardiovascular morbidity and mortality. The aim of this study was to investigate the effects of dipper (DHT) and nondipper status of hypertension on left atrial (LA), left ventricle (LV) systolic and diastolic functions using two-dimensional echocardiography (2D), tissue Doppler images (TDI) and strain imaging. Methods: A total of 60 patients and 20 healthy individuals were included in the study. The patients were separated two groups that dipper and nondippers (if their daytime ambulatory systolic and diastolic blood pressure did not decrease by at least 10% during the night). Left ventricle and LA strain values, diastolic function were obtained by 2D with automated software and compared between the groups. Results: Demographic variables of the groups were similar in our study.(such as age, gender, smoker, body mass index, lipid profile) Diastolic functions significantly impaired in NDHT group (E velosity and E/A ratio were significantly reduced, A velocity a significantly increased, p<0,005). Tissue Doppler measurements; Lateral Sm, Em, Septal Em were significantly reduced in NDHT group (p<0,005). Strain parameters of patients was seen to be significantly reduced in NDHT group (LV lateral S, LV septal S, LA lateral S, LA septal S , p<0,005). Conclusion: Patients with nondipper hypertension have decreased LV diastolic function, significantly changes of tissue Doppler and analysis of left ventricule and atrial strain, in comparison with dipper group. In our study, both atrial and ventricular strain evaluations were found to be significantly impaired in the NDHT group at the same time. Consequently LV-LA strain can be used for the assessment early knowledge of the target organ damage in patients with nondipper hypertension. Keywords: Hypertension, left atrial function, left ventricular function, tissue Doppler echocardiography, Strain, Strain rate
Corresponding Author: Yalim Z.