Syphilis with an increasing incidence is still a disease of worldwide. Untreated patients with syphilis might progress to a systemic illness that represents secondary syphilis. Clinical features of secondary syphilis are varied and named as great mimicker. This case was presented to emphasize the importance of considering syphilis in patients with atypical oral lesions and ulcerations to decrease the rates of the disease and to prevent the complications. Keywords: Oral ulcer, syphilis, treponema pallidum
Corresponding Author: Esra Pancar Yuksel