Two cases of isolated horizontal gaze palsy resulting from a demyelinating lesion are described. A brain magnetic resonance image confirmed in both cases that the lesions affected the region of the abducens nucleus in the posterior and medial part of the lower pons, either bilaterally or unilaterally. The patients were treated with intravenous methylprednisolone (1000mg/day for 5 days) and demonstrated marked improvement of horizontal gaze palsy. These results indicate that isolated horizontal gaze palsy may be the initial manifestation of relapse in cases of suspected multiple sclerosis.
Corresponding Author: Buket Ozkara