Objectives: Depression is related to poor clinical outcomes in patients with cardiovascular diseases like heart failure. However, we have no data demonstrating the association between depression and atrial fibrillation (AF). Methods: A total of 54 patients with AF and 52 patients without AF were enrolled in our study. Depression scores were assessed in 2 groups. Demographic and clinical information were recorded. Results: The mean age of the 2 groups was 61.94±9.49 years and 60.29±8.25 years, and 28% and 27% were female in the respective groups. In patients with AF, the depression score was higher than in the other group (19.7±1 vs. 10.1±2.3; p<0.001). The depression score was univariate and multiple linear regression analysis showed predictors for atrial fibrillation (0.999 [0.998–1.000]; p=0.002; 0.999 [0.998–1.000] p=0.007). The depression scale for predicting AF was determined to be 16.48, with 73% sensitivity and 61% specificity (area under the curve: 0.701; 95% confidence interval: 0.582–0.819). Conclusion: The depression score was higher in patients with AF, and it appears that there is an association between depression and AF. Depression may be a risk factor for AF.
Corresponding Author: Tarik Kivrak