The Association Between Lymphocyte/Neutrophil Ratio and Clinical Course in Intensive Care Patients
Atakan Tekinalp1, Özlen Bektaş2, Zümrüt Ela Arslan Kaşdoğan3, Hilal Kaymaz41Department of Hematology, Konya Training and Research Hospital, Internal Medicine, Konya, Turkey, 2Department of Hematology, Necmettin Erbakan University, Internal Medicine, Konya, Turkey, 3Department of Anesthesiology and Reanimation, Konya Training and Research Hospital, Konya, Turkey, 4Department of Internal Medicine, Konya Training and Research Hospital, Konya, Turkey
Objectives: Hemogram parameters and basic ratios, such as the lymphocyte-to-neutrophil ratio (LNR), in addition to other biochemical factors, have been examined for their potential role in the inflammatory process. In this study, the aim was to explore an association between hemogram parameters and clinical course in patient admitted to the intensive care unit (ICU). Methods: The data of 109 patients who were hospitalized for at least 10 days in the ICU were investigated retrospectively and divided into 2 groups: those who died in the ICU (n=68) and those who were transferred to a ward (n=41). Demographic features, hospitalization indications, length of time in the ICU, and laboratory data were analyzed using independent sample t-testing. Results: The LNR was significantly higher in the patients who were transferred to a ward (0.32±0.4 vs 0.16±0.20; p=0.03). There was no significant difference in the other variables, including age, days in ICU, NLR and mean platelet volume. LNR was an independent factor for the duration of stay in the ICU. Conclusion: The LNR may be helpful in the management and evaluation of patients in the ICU.
Cite This Article
Tekinalp A, Bektaş Ö, Arslan Kaşdoğan Z, Kaymaz H. The Association Between Lymphocyte/Neutrophil Ratio and Clinical Course in Intensive Care Patients. EJMI. 2018; 2(3): 156-160
Corresponding Author: Atakan Tekinalp